Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Carnitine and Vitamin C




Vitamin C

Research Papers that Mention the Interaction

The ascorbic acid plays an important part by activation of hydroxylation reactions in various biosyntheses, such as in that of tropocollagen, bile acids and carnitine.
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete  •  1984  |  View Paper
Liver carnitine level decreased from 249±16.1 nmoles/g (mean ±SEM) control value to 148±9.8 nmoles/g (59.4%) in ascorbic acid deficient guinea-pigs, while in the underfed (‘pair-fed’) group it decreased to 181±14.1 nmoles/g (72.6%).
Underfeeding also resulted in lower ascorbic acid levels; the depression of carnitine in the underfed animals could be prevented by an overdose (200 mg daily) of ascorbic acid.
Experientia  •  2005  |  View Paper
In skeletal muscle, vitamin C not only enhances carnitine biosynthesis but also protects cells against ROS generation induced by physical exercise.
Free radical biology & medicine  •  2005  |  View Paper
Ascorbic acid AsA ) is known to be required for the synthesis of carnitine.
Journal of nutritional science and vitaminology  •  1990  |  View Paper