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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“Prolonged incubation with phenylbutyrate, quinidine, and verapamil partially stimulated carnitine transport, while curcumin was ineffective.”
Pharmacological rescue of carnitine transport in primary carnitine deficiency“ Verapamil , cimetidine, carbamazepine, quinidine, and desipramine inhibited the carnitine uptake but required supratherapeutic concentrations, suggesting robustness of the carnitine uptake systems against xenobiotic challenge.”
“ Carnitine uptake was also noncompetitively inhibited by verapamil and quinidine, inhibitors of the multidrug resistance family of membrane transporters, suggesting that the carnitine transporter may share a functional motif with this class of transporters.”
“Both, uptake and efflux of L‐carnitine were inhibited by verapamil and unaffected by either extracellular pH or palmitoyl‐L‐carnitine.”
OCTN3: A Na+‐independent L‐carnitine transporter in enterocytes basolateral membrane“Tetraethylammonium, verapamil , valproate and pyrilamine significantly inhibited the carnitine uptake by BBM but not by BLM.”
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