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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Carnitine and Verapamil



Research Papers that Mention the Interaction

Prolonged incubation with phenylbutyrate, quinidine, and verapamil partially stimulated carnitine transport, while curcumin was ineffective.
Human mutation  •  2006  |  View Paper
Verapamil , cimetidine, carbamazepine, quinidine, and desipramine inhibited the carnitine uptake but required supratherapeutic concentrations, suggesting robustness of the carnitine uptake systems against xenobiotic challenge.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2006  |  View Paper
Carnitine uptake was also noncompetitively inhibited by verapamil and quinidine, inhibitors of the multidrug resistance family of membrane transporters, suggesting that the carnitine transporter may share a functional motif with this class of transporters.
Archives of biochemistry and biophysics  •  1999  |  View Paper
Both, uptake and efflux of L‐carnitine were inhibited by verapamil and unaffected by either extracellular pH or palmitoyl‐L‐carnitine.
Journal of cellular physiology  •  2005  |  View Paper
Tetraethylammonium, verapamil , valproate and pyrilamine significantly inhibited the carnitine uptake by BBM but not by BLM.
Biochimica et biophysica acta  •  2002  |  View Paper