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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carnitine
drug:
Pivampicillin
Research Papers that Mention the Interaction
“It is suggested that pivampicillin inhibits uptake of carnitine from the gut and may either directly or indirectly depress endogenous carnitine synthesis.”
Carnitine deficiency associated with long-term pivampicillin treatment: the effect of a replacement therapy regime.“These results demonstrate that in pivampicillin treatment the carnitine pool of erythrocytes also alters.”
“Short-term administration of pivampicillin and pivmecillinam resulted in a reduction of serum carnitine concentration and an increase in excretion of acylcarnitine in urine.”
“ Pivampicillin treatment reduced the carnitine concentrations in the liver of the 48 hr fasted rat to about 1/2 of the controls after 6 days.”
Reduced carnitine and ketogenesis in the pivampicillin treated rat.
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