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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carnitine
supplement:
Oleic Acid
Research Papers that Mention the Interaction
“In the presence of ATP and CoA, L‐carnitine stimulated oleic acid oxidation and suppressed the oleic acid‐induced depolarization, swelling, and Cyt.”
“These results suggest that L‐carnitine acts to maintain mitochondrial function and suppresses oleic acid‐mediated MPT through acceleration of β‐oxidation.”
L‐Carnitine suppresses oleic acid‐induced membrane permeability transition of mitochondria“Although insignificant, carnitine increased oleic acid oxidation to approximately 8%, and resulted in a decrease in endogenous lipid oxidation, which was 2–12% of the total substrates oxidized.”
“ Carnitine (about 0.1 mM) maximally stimulated State 3 respiration due to oleic and gondoic acids about three-fold (coenzyme A present), and coenzyme A (10--20 micrometer) stimulated about two-fold (carnitine present).”
“Moreover, when added to the medium perfusing livers from fed rats, carnitine stimulated ketogenesis from oleic acid.”
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