Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Carnitine and Octanoate

supplement:

Carnitine

Research Papers that Mention the Interaction

Addition of carnitine partially reversed the inhibitory effects of octanoate on acetyl-CoA carboxylase expression, suggesting that a metabolite of octanoate is involved in mediating this response.
Journal of lipid research  •  1997  |  View Paper
These data confirm the hypothesis that carnitine effects the in vivo oxidation of octanoate in colostrum-deprived piglets and suggest that the effects may be mediated by aiding the export of excess acetyl groups from muscle or by enhancing uptake of octanoate into liver mitochondria.
The Journal of nutrition  •  1995  |  View Paper
Carnitine addition prevented the inhibition of octanoate oxidation but not that of butyrate.
This inhibition of octanoate oxidation was also prevented by carnitine addition.
The Journal of biological chemistry  •  1984  |  View Paper
Although the addition of carnitine enhanced the oxidation of palmitate and octanoate by homogenates from both healthy and cardiomyopathic hamsters, the magnitude of the depression of oxidation (60–80%) in the myopathic homogenates was not influenced by carnitine.
Circulation research  •  1974  |  View Paper