supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Six … ER niacin led to a significant reduction in mean adipocyte size associated with increased insulin sensitivity in … adipocytes and gene expression changes including increased adiponectin, C/EBPalpha, C/EBPdelta, PPARgamma and decreased carnitine palmitoyl transferase 2, hormone sensitive lipase, nicotinic acid … (GPR109B) and fatty-acid synthase mRNA expression.”
Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.“ResultsRats of the obese niacin group had higher concentrations of total carnitine in plasma, skeletal muscle and liver, higher mRNA and protein levels of … concentrations of total carnitine in plasma and skeletal muscle than lean rats (P < 0.05).ConclusionThe results show for the first time that niacin … carnitine ….”
Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback