Possible Interaction: Carnitine and Lysine

“Conversion of lysine to carnitine may be impaired in malnutrition.”

“… L-lysine orally to … in plasma carnitine levels within 6 h followed by a further rise by 48 h. Levels remained high up to 72 h. Similar changes … if blood was sampled without lysine load or after administering a load of other amino acids such as tryptophan or threonine.”

“She commenced dietary carnitine and her intake of lysine and tryptophan were reduced at the age of 4weeks.”

“In Experiment 2, rats given lysine had significantly lower plasma total carnitine concentration, and significantly greater skeletal muscle and plasma trimethyllysine concentration relative to controls.”

“We conclude that dietary potassium and lysine, and oral lysine , have a significant effect upon the distribution of carnitine and trimethyllysine in rats.”