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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carnitine and Levocarnitine





Research Papers that Mention the Interaction

L-carnitine supplementation resulted in significant carnitine plasma level increase by week 4.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  2012  |  View Paper
L-Carnitine treatment prevented this fall in plasma carnitine and resulted in greater increases in excretion of acylcarnitines.
Journal of Inherited Metabolic Disease  •  2005  |  View Paper
Intravenous L-carnitine treatment increased plasma carnitine concentrations, improved patient-assessed fatigue, and may prevent the decline in peak exercise capacity in hemodialysis patients.
L-Carnitine supplementation increased plasma carnitine concentrations, but did not affect VO(2max) in either study.
American journal of kidney diseases : the official journal of the National Kidney Foundation  •  2001  |  View Paper
After L-carnitine supplementation in eleven patients with hypocarnitinemia, the concentrations of carnitine were significantly increased.
Journal of Korean medical science  •  1997  |  View Paper
By contrast, total and free carnitine levels were markedly increased (p < 0.01) after supplementation with L-carnitine.
Biochemical and biophysical research communications  •  1992  |  View Paper
Furthermore, in a randomly-selected hemodialysis population, L-carnitine injection at the dose of 20 mg/kg results in significant increases in blood (and perhaps tissue) carnitine levels, but this is not associated with any major effects on lipid profiles.
Kidney international  •  1990  |  View Paper
When L-carnitine was added to the dialysate, total carnitine was observed to significantly increase in the group receiving 4 g.(ABSTRACT TRUNCATED AT 250 WORDS)
Nephron  •  1989  |  View Paper
This work suggest that the daily administration during a long period, of 2 g of L-carnitine guarantee in a healthy subject blood carnitine concentrations superior to the normal levels.
Diabete & metabolisme  •  1983  |  View Paper
In contrast, treatment with L-carnitine increased plasma carnitine levels by 80% and the skeletal muscle carnitine content by 50%.
European journal of pharmacology  •  2010  |  View Paper
After intestinal absorption, L- and D-carnitine is transferred to organs whose metabolism is dependent on fatty acid oxidation, such as heart and skeletal muscle, and D-carnitine competitively depletes muscle level of L-carnitine.
There is some evidence that L-carnitine and D-carnitine compete for uptake in small intestine and tubular re-absorption in kidneys.
Whereas L-carnitine is found to be essential for the oxidation of fatty acids, D-carnitine causes a depletion of L-carnitine , and hindered fatty acid oxidation and energy formation.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova  •  2005  |  View Paper
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