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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carnitine
drug:
Dexamethasone
Research Papers that Mention the Interaction
“…,LCAR (a) suppressed the lipopolysaccharide‐stimulated release of tumor necrosis factor α and interleukin‐12 from primary human monocytes in a GC‐like fashion, (… the GC‐responsive promoters, (c) triggered nuclear translocation of green fluorescent protein (GFP)‐fused GR, and (d) reduced the whole cell binding of [3H]‐dexamethasone ….”
Modulatory Effects of l‐Carnitine on Glucocorticoid Receptor Activity“Millimolar concentrations of l‐carnitine , which were not cytotoxic in vitro, significantly reduced the whole cell binding of [3H]dexamethasone to GRα by decreasing the affinity of this receptor for its steroid ligand.”
“In heart and kidney, but not in liver, dexamethasone significantly increased total carnitine concentration.”
Effects of dexamethasone on carnitine metabolism in liver and extrahepatic tissues
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