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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carnitine
drug:
Cyclophosphamide
Research Papers that Mention the Interaction
“Moreover, some MS treatments (including interferons, mitoxantrone and cyclophosphamide ) can interfere with the carnitine network and indirectly induce fatigue syndrome [3].”
Carnitine serum levels and levocarnitine administration in multiple sclerosis patients treated with natalizumab“Interestingly, carnitine supplementation completely reversed all the biochemical, histopathological and gene expression changes induced by CP and IFO to the control values, except CPT I mRNA, and protein expression remained inhibited by IFO.”
Inhibition of Gene Expression of Carnitine Palmitoyltransferase I and Heart Fatty Acid Binding Protein in Cyclophosphamide and Ifosfamide-Induced Acute Cardiotoxic Rat Models“3) Carnitine supplementation attenuates CP but not IFO-induced inhibition of OCTN2 mRNA and protein expression in heart and kidney tissues.”
“Prototypes of anticancer drugs that alter carnitine system are doxorubicin, cisplatin, carboplatin, oxaliplatin, cyclophosphamide and ifosfamide.”
Role of carnitine in cancer chemotherapy-induced multiple organ toxicity.
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