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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“ Clozapine decreases renal reabsorption and increases urinary excretion of L‐Car.”
“Our results reveal that clozapine inhibits L‐Car uptake in MDCK‐hOCTN2 cells with an IC50 value of 1.78&mgr;M. Additionally, clozapine significantly reduces the uptake of L‐Car in HK‐2 cells, mouse primary cultured proximal tubular (mPCPT) cells and HepG2 cells.”
Clozapine‐induced reduction of l‐carnitine reabsorption via inhibition/down‐regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice
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