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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Carnitine
drug:
Cephaloridine
Research Papers that Mention the Interaction
“A potential mechanism for the development of carnitine deficiency is competition between cephaloridine and carnitine for the renal reabsorptive process.”
β-Lactam Antibiotics as Substrates for OCTN2, an Organic Cation/Carnitine Transporter*“This suppression was inhibited by cephaloridine , an inhibitor of carnitine uptake into mitochondria.”
Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition.“It has been demonstrated recently that cephaloridine (Cld) inhibits the tubular reabsorption of filtered carnitine (Carn) in the rabbit kidney.”
“Cld inhibited CFPO in a dose-dependent manner, up to 100% at 2000 micrograms/ml; this effect was reduced by increasing … 30%; 5) in vivo Cld increased mitochondrial-free carnitine in the in situ kidney by 100%; and 6) in vivo Cld … carnitine from 0 +/- 0 … AT 250 WORDS)”
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