“At 10(-2) M azelaic acid , however, some swelling of the mitochondria occurred which was significantly increased by the addition of carnitine.”
“We conclude that carnitine may reduce the time or concentration needed for azelaic acid to have a toxic effect on the malignant melanocyte.”
“We investigated the possibility that the addition of carnitine to the medium may increase the transport of azelaic acid into the mitochondria and thereby increase its cytotoxic effect.”