supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Carmustine
supplement:
Resveratrol
Research Papers that Mention the Interaction
“Drug combination of BCNU + Resveratrol decreased the cell survival and NECTIN-4 expressions in 5-FU-R cells and NECTIN-4-over-expressed cells.”
NECTIN-4 increased the 5-FU resistance in colon cancer cells by inducing the PI3K–AKT cascade“Combined application of BCNU and Res caused more apoptosis in 5-FU sensitive cells in comparison to individual treatment.”
“Fifty percent cell death were noted in parental cells when 18 μmol/L of Res was associated with fixed concentration (20 μmol/L) of BCNU , but a much lower concentration of Res (8 μmol/L) was needed to achieve the same effect in 5-FU resistant cells.”
“In addition, the combined application of BCNU and Res caused a significant decrease of major DNA base excision repair components in 5-FU sensitive cells.”
“Increased genotoxicity and apoptosis were observed in resistant cells after combined application of BCNU and Res in comparison to untreated or parental cells.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback