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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carmustine
supplement:
Histidine
Research Papers that Mention the Interaction
“The rate of incorporation of histidine-2 -14C into the nucleic acid purines of leukemic cells was inhibited by BCNU.”
Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.“ L-Histidinol enhanced the ability of bis-chloroethylnitrosourea , 5-fluorouracil, and 1-beta-D-arabinofuranosulcytosine to reduce the number of lung foci.”
Improved treatment of disseminated B16f10 melanoma in mice with anticancer drugs in combination with L-histidinol.“Dose-response studies showed that L-histidinol conferred dose-dependent, synergistic improvements on the capacities of both BCNU and cisDDP to increase the life-span of DBA/2J mice bearing P388 leukemia.”
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