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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cardiotonic Agents and Calcium Supplement

Research Papers that Mention the Interaction

Thus, calcium inhibits the cardiotonic actions of certain beta-adrenergic agonists, most likely by interfering with signal transduction through the beta-adrenergic receptor complex.
Chest  •  1992  |  View Paper
In the intact cat, calcium and aminophylline also produce significant elevations in the content of glucose-6-phosphate in the right and left ventricles and left auricle concomitant with their eardiotonic action.
Biochemical pharmacology  •  1962  |  View Paper
In addition, this effect was inhibited by 2 mg/mL nifedipine, suggesting that the cardiotonic mechanism could be responsible for accelerating the inflow of calcium ions.
Natural product research  •  2012  |  View Paper
Cardioprotection activates a number of signaling pathways that reduce the level of triggers (reactive oxygen species and calcium ) or enhances inhibitors of the mitochondrial permeability transition pore at the start of reperfusion.
Biochimica et biophysica acta  •  2011  |  View Paper
We propose that calcium may be an important mediator in eliciting this cardioprotection.
Circulation  •  1997  |  View Paper
Mg proved to be in vitro a potent antiarrhythmic and cardioprotective agent which is likely to exert its beneficial effects via antagonism of calcium.
Magnesium research  •  1991  |  View Paper
Positive inotropic agents increase the rate of calcium accumulation wheras the negative inotropic drug, lignocaine, depresses the rate of calcium accumulation.
Irish journal of medical science  •  1969  |  View Paper