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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cardiotonic Agents
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Thus, calcium inhibits the cardiotonic actions of certain beta-adrenergic agonists, most likely by interfering with signal transduction through the beta-adrenergic receptor complex.”
Calcium inhibits the cardiac stimulating properties of dobutamine but not of amrinone.“In the intact cat, calcium and aminophylline also produce significant elevations in the content of glucose-6-phosphate in the right and left ventricles and left auricle concomitant with their eardiotonic action.”
“In addition, this effect was inhibited by 2 mg/mL nifedipine, suggesting that the cardiotonic mechanism could be responsible for accelerating the inflow of calcium ions.”
Composition of fatty oils from Semen Ziziphi Spinosae and its cardiotonic effect on isolated toad hearts“ Cardioprotection activates a number of signaling pathways that reduce the level of triggers (reactive oxygen species and calcium ) or enhances inhibitors of the mitochondrial permeability transition pore at the start of reperfusion.”
“We propose that calcium may be an important mediator in eliciting this cardioprotection.”
“Mg proved to be in vitro a potent antiarrhythmic and cardioprotective agent which is likely to exert its beneficial effects via antagonism of calcium.”
“ Positive inotropic agents increase the rate of calcium accumulation wheras the negative inotropic drug, lignocaine, depresses the rate of calcium accumulation.”
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