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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cardiac Glycosides and Verapamil

Research Papers that Mention the Interaction

Pharmaceuticals that antagonize these fluxes, including glyburide and verapamil , also inhibit inflammasome activation by cardiac glycosides.
The Journal of Biological Chemistry  •  2019  |  View Paper
Because digoxin toxicity is frequently associated with severe morbidity and mortality, close monitoring of clinical and laboratory signs are mandatory whenever the cardiac glycoside is coadministered with quinidine, verapamil , amiodarone, nifedipine, and indomethacin.
Pediatrics  •  1985  |  View Paper
Although coadministration of verapamil and digoxin results in significant increases in plasma glycoside concentrations, evidence of digitalis toxicity appears to be infrequent with this combination.
In addition, the dose of glycoside required to produce electrophysiologic toxicity was significantly increased by verapamil.
Pharmacology  •  1984  |  View Paper