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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cardiac Glycosides
drug:
Verapamil
Research Papers that Mention the Interaction
“Pharmaceuticals that antagonize these fluxes, including glyburide and verapamil , also inhibit inflammasome activation by cardiac glycosides.”
Inflammasome inhibition blocks cardiac glycoside cell toxicity“Because digoxin toxicity is frequently associated with severe morbidity and mortality, close monitoring of clinical and laboratory signs are mandatory whenever the cardiac glycoside is coadministered with quinidine, verapamil , amiodarone, nifedipine, and indomethacin.”
“Although coadministration of verapamil and digoxin results in significant increases in plasma glycoside concentrations, evidence of digitalis toxicity appears to be infrequent with this combination.”
“In addition, the dose of glycoside required to produce electrophysiologic toxicity was significantly increased by verapamil.”
Effects of verapamil on the arrhythmogenic action of acetylstrophanthidin.
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