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Last Updated: 2 years ago

Possible Interaction: Cardiac Glycosides and Tetrodotoxin

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supplement:

Cardiac Glycosides

drug:

Tetrodotoxin

Research Papers that Mention the Interaction

“In the presence of tetrodotoxin to block the action potentials, both zero K(+)-induced depolarization and rebound hyperpolarization were blocked by the cardiac glycoside strophanthidin.”

Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons.

Journal of neurophysiology • 2012 | View Paper

“ CGs decreased the threshold for activation of Ca2+ spikes (recorded in TTX and TEA) without enhancing the spikes themselves, indicating that a voltage-dependent subthreshold conductance might be involved.”

Sodium-potassium pump inhibitors increase neuronal excitability in the rat hippocampal slice: role of a Ca2+-dependent conductance.

Journal of neurophysiology • 1987 | View Paper

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