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Discover Supplement-Drug Interactions

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Possible Interaction: Cardiac Glycosides and Spironolactone

Research Papers that Mention the Interaction

We also observed that the putative mineralocorticoid antagonists, spironolactone and its major metabolite canrenone, antagonize binding of cardiotonic steroids to Na/K-ATPase in a competitive manner and also ameliorate experimental uremic cardiomyopathy induced by partial nephrectomy.
Journal of hypertension : open access  •  2013  |  View Paper