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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cardiac Glycosides and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

The cardiac glycoside ouabain, which is a specific inhibitor of the Na+,K+-pump, confers dramatic protection from the cytotoxic effects of doxorubicin (Adriamycin).
Cancer research  •  1988  |  View Paper
This observation combined with the initial work of Arena et al. (1972) that strophanthin may inhibit myocardial adriamycin uptake, makes the inhibition of adriamycin uptake by cardiac glycosides an area warranting further study.
British Journal of Cancer  •  1977  |  View Paper