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Last Updated: a year ago

Possible Interaction: Cardiac Glycosides and Calcium Supplement

Research Papers that Mention the Interaction

The growth inhibiting effect of the glycoside on HL-60 cells was promoted by calcium and was inhibited in the presence of zinc, which support involvement of endonuclease activation in the glycoside-induced apoptosis.
Life sciences  •  1996  |  View Paper
Cardiac glycosides exert a positive inotropic effect by inhibiting sodium pump (Na,K-ATPase) activity, decreasing the driving force for Na+-Ca++ exchange, and increasing cellular content and release of Ca++ during depolarization.
The Journal of clinical investigation  •  1996  |  View Paper
Cardiac glycosides inhibit the membrane sodium-potassium pump raising the concentration of intracellular sodium which is then available for exchange with extracellular calcium by another membrane transport system.6 Thus cardiac glycosides can increase intracellular calcium and enhance contractility.
Postgraduate medical journal  •  1989  |  View Paper
The inotropic effect of cardiac glycosides may also depend on the calcium that is bound to these stores.
The American journal of physiology  •  1989  |  View Paper
It is inferred that cardiosteroids should be combined with small amounts of calcium in order to attain a positive inotropic effect.
Biulleten' eksperimental'noi biologii i meditsiny  •  1985  |  View Paper
The possible involvement of calcium increase in the genesis of cardiac glycoside induced myocardial cell necrosis is discussed.
Acta morphologica Hungarica  •  1985  |  View Paper
The data strongly suggest that calcium entry into cells is a major mediator of the renin inhibitory effect and of the renal vasoconstriction induced by cardiac glycosides.
The American journal of physiology  •  1984  |  View Paper
THe synergistic effects between calcium and the therapeutic and toxic actions of the cardiac glycosides have suggested that a way of treating digitalis intoxication could be through a decrease in free plasma calcium.
Archivos del Instituto de Cardiologia de Mexico  •  1981  |  View Paper
C.G. influence the Ca content and Ca movements of smooth muscles.
Nihon Heikatsukin Gakkai zasshi  •  1980  |  View Paper
The CG are thought to alter the Ca binding in this pool, thus rendering depolarization more effective in releasing Ca++.
Recent advances in studies on cardiac structure and metabolism  •  1976  |  View Paper
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