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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbon Monoxide
supplement:
Riboflavin
Research Papers that Mention the Interaction
“ CO production by human placenta microsomes increased four-fold with riboflavin and five-fold with PQQ.”
“In rat brain microsomes, riboflavin and PQQ increased respective CO production ~four-fold and two-fold, compared to baseline.”
Riboflavin and pyrroloquinoline quinone generate carbon monoxide in the presence of tissue microsomes or recombinant human cytochrome P-450 oxidoreductase (CPR); implications for possible roles in gasotransmission.“Both stimulations by riboflavin were completely blocked by carbon monoxide.”
Reduction of epoxy derivatives of benzo(a)pyrene by microsomal cytochrome P-450.“The stimulatory effect of FMN or methyl viologen on the xanthine oxidase-supported N-oxide reduction was dependent on the amount of added xanthine oxidase and was completely blocked under an atmosphere of carbon monoxide.”
“ Abstract FMN or methyl viologen stimulated anaerobic reduction of tertiary amine N-oxides by liver microsomes and this stimulatory effect was completely inhibited by carbon monoxide.”
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