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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbon Monoxide
supplement:
Phosphatidylinositol 4,5-Diphosphate
Research Papers that Mention the Interaction
“ CO directly inhibits Kir2.3 by interfering with its interaction with the second messenger phosphatidylinositol (4,5)-bisphosphate (PIP2).”
Carbon monoxide inhibits inward rectifier potassium channels in cardiomyocytes.“The gasotransmitter carbon monoxide has been shown to regulate Kir channel activity by altering channel– PIP2 interactions.”
Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)
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