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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carbon Monoxide and Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

CO directly inhibits Kir2.3 by interfering with its interaction with the second messenger phosphatidylinositol (4,5)-bisphosphate (PIP2).
Nature communications  •  2014  |  View Paper
The gasotransmitter carbon monoxide has been shown to regulate Kir channel activity by altering channel– PIP2 interactions.
The Journal of Biological Chemistry  •  2018  |  View Paper