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Last Updated: a year ago

Possible Interaction: Carbon Monoxide and Ferrous

supplement:

Ferrous

Research Papers that Mention the Interaction

Consistently, we observed increased affinity (∼5-fold) and faster association (∼10-fold) of CO to the ferrous heme at physiological AdoMet concentrations.
The Journal of Biological Chemistry  •  2015  |  View Paper
UV/visible spectroscopy was used to confirm that CO induces small spectral shifts in ferrous MPO, and Fourier transform infrared difference spectroscopy showed definitively that these arose from formation of a heme ferrous-CO compound.
Biochemistry  •  2010  |  View Paper
In MV-CO, the frequency of the stretch mode of CO bound to ferrous heme a(3) decreases from 1965.3 cm(-1) at pH* </=7 to 1963.7 cm(-1) at pH* 9.3.
Biochimica et biophysica acta  •  2004  |  View Paper
However, reaction of CO with the Fe(II) complexes (k(on) = 3.6 x 10(7) M(-1) s(-1) for Fe(II)(TPPS)) displays negative Delta and Delta values, consistent with a mechanism dominated by activation rather than diffusion terms.
Journal of the American Chemical Society  •  2001  |  View Paper