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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbocysteine
supplement:
Phenylalanine
Research Papers that Mention the Interaction
“The PAH mutant proteins (R158Q, I174T and R408W) that result in the classical phenylketonuria (…) phenotype expressing 0.2-1.8% of the wild type PAH activity when using phenylalanine as substrate were found to have <0.…% of the wild type PAH activity when SCMC was used as the substrate.”
The activity of wild type and mutant phenylalanine hydroxylase with respect to the C-oxidation of phenylalanine and the S-oxidation of S-carboxymethyl-L-cysteine.“Analysis of the Dixon plots revealed that both Phe and SCMC competitively inhibited each other's oxidation.”
Phenylalanine 4-Monooxygenase and the S-Oxidation of S-Carboxymethyl-L-cysteine
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