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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbimazole
supplement:
Iodides
Research Papers that Mention the Interaction
“2 In all patients there was a marked reduction in iodide binding with carbimazole doses as low as 5 to 10 mg daily.”
Intrathyroidal iodide binding rates and plasma methimazole concentrations in hyperthyroid patients on small doses of carbimazole.“With 2.5 mg carbimazole , there was a profound discharge of the trapped iodide in both groups in the iodine-deficient area.”
“High doses of iodide (30 mg three times daily) in combination with carbimazole led to a rapid 45% decline in thyroxine secretion.”
“The findings indicate that carbimazole enhances the sensitivity of the normal thyroid gland toward pharmacological doses of iodide .–High doses of iodide together with carbimazole reduced the secretion of non‐hormonal iodine (which can be taken as an index of thyroglobulin hydrolysis) by only 31%.”
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