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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbenoxolone
supplement:
Glucose
Research Papers that Mention the Interaction
“However, carbenoxolone reduced the glucose production rate during hyperglucagonemia in diabetic patients (1.90 +/- 0.2 vs. 1.53 +/- 0.3 mg/kg x min; P < 0.05).”
Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.“We infer that carbenoxolone , by inhibiting hepatic 11 beta-reductase and reducing intrahepatic cortisol concentration, increases hepatic insulin sensitivity and decreases glucose production.”
“In perfused livers, carbenoxolone (200–300 μM) increased oxygen consumption, glucose production and glycolysis from endogenous glycogen.”
Metabolic effects of carbenoxolone in rat liver“ Carbenoxolone significantly decreased the glucose uptake and the incorporation of glucose into triglycerides and CO2 in rat epididymal fat pads.”
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