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“ Carbenoxolone or a Cx43-selective peptide blocker also reduced calcium rise, consistent with involvement of gap junction-mediated mechanisms in addition to voltage-gated calcium channels.”
“However, resting fura-2 ratio (indicator for intracellular Ca2+ concentration) and amplitude of the Ca2+ transient were significantly (P < 0.05) reduced by CBX in diabetic rats but not in controls.”