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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbenoxolone
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“ CBX treatment led to a gradual decrease in both basal and in corticotropic releasing hormone (CRH)-stimulated plasma ACTH concentrations and CRH-stimulated serum cortisol concentrations, without side effects.”
“The findings suggest that CBX inhibits ACTH secretion from canine pituitary tumors, resulting in lower cortisol concentrations.”
“We previously reported that carbenoxolone (CBX), an inhibitor of 11HSD, suppressed ACTH secretion from the pituitary gland, and decreased cortisol concentrations in healthy dogs.”
Carbenoxolone Disodium Treatment for Canine Pituitary-Dependent Hyperadrenocorticism“The results of this study suggested that CBX inhibits ACTH secretion from pituitary due to altered 11HSD expressions, and is potentially useful for the treatment of canine Cushing’s disease.”
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