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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbenicillin
supplement:
Epinephrine
Research Papers that Mention the Interaction
“At antibiotic concentrations that inhibited platelet function by more than 80%, the affinity of platelet alpha-adrenergic receptors for the alpha-adrenergic antagonist, [(3)H]dihydroergocryptine, and for epinephrine was reduced twofold by carbenicillin and sixfold by penicillin G (P < 0.01).”
Carbenicillin and penicillin G inhibit platelet function in vitro by impairing the interaction of agonists with the platelet surface.“ Carbenicillin disodium penetrated in inhibitory concentrations only when given subconjunctivally in combination with epinephrine.”
Intraocular penetration of semisynthetic penicillins: methicillin, cloxacillin, ampicillin, and carbenicillin studies in experimental animals with a review of the literature.
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