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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbamazepine
supplement:
Tryptophan
Research Papers that Mention the Interaction
“It was found that carbamazepine had direct competition with l-tryptophan , a probe for the indole-benzodiazepine site of HSA, but allosteric interactions with probes for the warfarin, tamoxifen and digitoxin sites.”
Chromatographic analysis of carbamazepine binding to human serum albumin.“Furthermore, treatment with carbamazepine lowered the concentration of tryptophan bound to plasma proteins and elevated the brain serotonin values.”
Effects of carbamazepine treatment on pain threshold values and brain serotonin levels in rats.
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