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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Carbamazepine and Tryptophan

supplement:

Tryptophan

Research Papers that Mention the Interaction

It was found that carbamazepine had direct competition with l-tryptophan , a probe for the indole-benzodiazepine site of HSA, but allosteric interactions with probes for the warfarin, tamoxifen and digitoxin sites.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences  •  2005  |  View Paper
Furthermore, treatment with carbamazepine lowered the concentration of tryptophan bound to plasma proteins and elevated the brain serotonin values.
Pharmacology  •  1997  |  View Paper