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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carbamazepine and Folic Acid


Folic Acid

Research Papers that Mention the Interaction

BackgroundAntiepileptic drugs (AEDs) like phenytoin (PHE), carbamazepine (CBZ), barbiturates and valproic acid (VPA) interfere with folic acid absorption and metabolism, which in turn can be the cause of adverse pregnancy outcome.
Journal of Neurology  •  2008  |  View Paper
All women taking valproate and carbamazepine are advised to take 4 mg/day of folic acid at least one month before pregnancy and during the first trimester.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke  •  2003  |  View Paper
Results– The patients on CBZ had significantly lower concentrations of fasting S‐FA and E‐FA than the controls (P=0.0004, P=0.003, respectively).
Acta neurologica Scandinavica  •  2001  |  View Paper
We recommend combination therapy of carbamazepine and folic acid in the treatment of patients, especially elderly patients with lesions involving the mandibular division of the trigeminal nerve.
Nigerian medical journal : journal of the Nigeria Medical Association  •  2015  |  View Paper