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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Carbamazepine
supplement:
Folic Acid
Research Papers that Mention the Interaction
“BackgroundAntiepileptic drugs (AEDs) like phenytoin (PHE), carbamazepine (CBZ), barbiturates and valproic acid (VPA) interfere with folic acid absorption and metabolism, which in turn can be the cause of adverse pregnancy outcome.”
Spontaneous abortion and the prophylactic effect of folic acid supplementation in epileptic women undergoing antiepileptic therapy“All women taking valproate and carbamazepine are advised to take 4 mg/day of folic acid at least one month before pregnancy and during the first trimester.”
“Results– The patients on CBZ had significantly lower concentrations of fasting S‐FA and E‐FA than the controls (P=0.0004, P=0.003, respectively).”
“We recommend combination therapy of carbamazepine and folic acid in the treatment of patients, especially elderly patients with lesions involving the mandibular division of the trigeminal nerve.”
Early response to medical treatment of trigeminal neuralgia in a Nigerian population
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