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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carbachol and Tretinoin

supplement:

Tretinoin

Research Papers that Mention the Interaction

Adding carbachol which is a cholinergic agonist to the ATRA treatment resulted in an increase of a granulocytic differentiation marker (CD11b) as compared with ATRA treatment alone (p<0.05), indicating that cholinergic activation enhanced ATRA in inducing NB-4 maturation.
The combination of carbachol and ATRA treatment for 72h also resulted in decreased viability and increased cleaved caspase-3 expression when compared with ATRA treatment alone (p<0.05).
Blood cells, molecules & diseases  •  2016  |  View Paper
The addition of RA also significantly reduced the effect of carbachol on NLRP3 inflammasomes.
Pharmacological reports : PR  •  2021  |  View Paper