Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Carbachol and Secretin

supplement:

Secretin

Research Papers that Mention the Interaction

When secretin was added to 1 mM carbachol , there was a slight increase in zymogen activation, but no change in the secretion of amylase or chymotrypsin.
American journal of physiology. Gastrointestinal and liver physiology  •  2005  |  View Paper
Oxygen uptake increased further when carbamylcholine was superimposed on secretin.
The American Journal of Digestive Diseases  •  2005  |  View Paper
Secretin inhibited insulin secretion induced by carbachol and LIPNA, whereas VIP potentiated L-IPNA-induced insulin secretion and had no influence on the effect of carbachol.
Diabetologia  •  2004  |  View Paper
Combination of secretin with carbachol or caerulein increased the amylase output to about 40%.
When secretin was combined with carbachol or caerulein, granule depletion, originally confined to small groups of neighbouring acini, spread to form large areas of degranulated cells, sometimes comprising a whole section of a lobule.
Cell and Tissue Research  •  2004  |  View Paper
3 The physiological concentration of secretin (50 pm) had a relatively weak effect on IKs (160 % increase), which was significantly enhanced by transient co‐stimulation with carbachol (CCh) (10 μm).
The Journal of physiology  •  2001  |  View Paper
Synergistic effects were found between carbachol and either secretin or vasoactive intestinal peptide in the regulation of DOPA (dihydroxyphenylalanine) synthesis.
Journal of neurobiology  •  2000  |  View Paper
In in vitro study, a combined administration of secretin and carbachol or cholecystokinin octapeptide (CCK-8) to the culture medium of chief cells potentiated pepsinogen secretion.
Biological & pharmaceutical bulletin  •  1995  |  View Paper
Stimulation of amylase release by increasing concentrations of carbamylcholine resulted in a dose-dependent recruitment of secreting acini as well as in a time-dependent enhancement in the response of individual acini.
The American journal of physiology  •  1988  |  View Paper
In addition, BPP inhibited the potentiation of amylase secretion caused by the combination of carbachol plus secretin or vasoactive intestinal peptide.
The American journal of physiology  •  1987  |  View Paper
A combination of carbachol and secretin (4.25 nmol kg-1) enhanced plasma glucagon levels to 1.22 +/- 0.07 ng ml-1.
Acta physiologica Scandinavica  •  1986  |  View Paper
Show More