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Last Updated: 5 years ago

Possible Interaction: Carbachol and Quinidine

supplement:

Quinidine

Research Papers that Mention the Interaction

“ Quinidine but not sotalol or metoprolol prolonged the action potential duration and abolished arrhythmic activity induced by carbachol.”
Journal of the American Heart Association  •  2018  |  View Paper
“In some preparations, quinidine at concentrations of 5 μmol/l and higher slowed the spontaneous activity by its direct membrane action even in the presence of carbachol.”
“In the presence of 0.1 μmol/l carbachol , the spontaneous activity of the atrioventricular nodal preparations was markedly inhibited, whereas subsequent addition of 1, 5 and 20 μmol/l quinidine restored automaticity in a concentration-dependent manner.”
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
“ Quinidine was found to inhibit catecholamine release from the medulla of perfused adrenal glands induced by carbamylcholine.”
Research communications in chemical pathology and pharmacology  •  1979  |  View Paper