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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carbachol and Prolinedithiocarbamate

Research Papers that Mention the Interaction

Either M3 cholinergic receptor antagonist (10(-5) mol/L atropine) or NF-kappaB inhibitor (10(-2) mol/L PDTC ) could obviously inhibit the activation of NF-kappaB and the chemokine MOB-1, MCP-1 mRNA expression induced by carbachol (P<0.05).
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban  •  2004  |  View Paper
The addition of 10−2 mol/L PDTC resulted in a significant decrease of NF-κB activities in pancreatic acinar cells after treated with high concertrations of carbachol (10−3 mol/L) in vitro, but the intracelluar trypsinogen activity was not obviously inhibited (P>0.05).
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban  •  2008  |  View Paper
The action of carbachol was inhibited by the intracellular Ca(++) chelator BAPTA-AM, the PKC inhibitor GF109203X, and the NF-kappaB inhibitor PDTC.
Biochemical and biophysical research communications  •  1999  |  View Paper