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Last Updated: a year ago

Possible Interaction: Carbachol and Niacin

supplement:

Niacin

Research Papers that Mention the Interaction

Responses to carbachol suggested interactions between nicotinic and excitatory muscarinic effects.
The Journal of comparative neurology  •  1999  |  View Paper
In contrast, carbachol produced a further rise of [Ca++]i, attributable to activation of both nicotinic and muscarinic receptors, because it was reduced (but not abolished) by mecamylamine (1 microM) and was observed when muscarine was used as the agonist.
The Journal of pharmacology and experimental therapeutics  •  1997  |  View Paper
The effect of carbachol was also mimicked by the nicotinic agonists, nicotine (100 microM) and epibatidine (10 microM).
Neuroscience  •  2000  |  View Paper
Carbachol , which activates both nicotinic and muscarinic receptors, produces 12–19-fold increases in PNMT mRNA and a 22-fold increase in epinephrine release.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  1994  |  View Paper
The depressant effect of carbachol was blocked by the nicotinic antagonists hexamethonium, mecamylamine and d‐tubocurarine but not by atropine.
The Journal of physiology  •  1984  |  View Paper
The activation of nicotinic cholinoreceptors with carbachol , suberildicholine and tetramethylammonium evoked depolarization with an increase in membrane conduction.
Neirofiziologiia = Neurophysiology  •  1979  |  View Paper
3 Nicotinic acid and alloxanate inhibited enzyme secretion stimulated by carbachol.
British journal of pharmacology  •  1977  |  View Paper