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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbachol
supplement:
Masoprocol
Research Papers that Mention the Interaction
“At anti-proliferative concentrations, NDGA and CA significantly inhibited intracellular Ca2+ release induced by carbachol , a known intracellular Ca2+ agonist in the tumor cells.”
Intracellular Ca2+ mediates lipoxygenase-induced proliferation of U-373 MG human astrocytoma cells“The addition of nordihydroguaiaretic acid (10(-6) M) or indomethacin (10(-6) M) partially attenuated the arachidonic acid-enhanced secretory responsiveness to carbachol.”
Arachidonic acid increases cholinergic secretory responsiveness of ferret tracheal glands.“Mepacrine and NDHGA , but not indomethacin or imidazole, inhibited contractions induced by carbachol and relaxed tonic contractions to KCl (60 mM).”
“The lipoxygenase inhibitors BW755C and nordihydroguaiaretic acid inhibited [3H]InsP production in response to glucose, carbamylcholine , and fatty acids.”
“Quinacrine and nordihydroguaiaretic acid abolished the relaxant effect of carbachol and flurbiprofen had no effect.”
“Removal of the endothelium or a 30-min pre-treatment of the strips with a substance that has lipoxygenase-inhibitor activity nordihydroguaiaretic acid , NDGA, 10(-5) M) abolished the relaxant effect of carbachol and partially blocked the relaxant effect of Gb.”
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