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Last Updated: 3 years ago

Possible Interaction: Carbachol and Iodides

supplement:

Iodides

Research Papers that Mention the Interaction

I- also inhibited the stimulation by TSH, 12-O-tetradecanoyl phorbol-13-acetate, carbachol , and ionophore A23187 of 32P incorporation into phospholipids.
Preincubation of dog thyroid slices for 1 h with iodide (10(-4) M) inhibited TSH-, (Bu)2cAMP-, carbachol- , methylene blue-, 12-O-tetradecanoyl phorbol-13-acetate-, ionophore A23187-, prostaglandin E1-, and cholera toxin-stimulated glucose oxidation.
Endocrinology  •  1989  |  View Paper
In thyroid cells, carbachol inhibited uptake and increased efflux of iodide within minutes.
Endocrinology  •  1988  |  View Paper
In dog thyroid slices, iodide greatly inhibited H2O2 generation stimulated by thyrotropin and by carbamylcholine.
Iodide decreased the production of intracellular signals induced by TSH and carbamylcholine but it also inhibited the action of probes of these intracellular signals (dibutyryl cAMP, forskolin, ionomycin, phorbol-myristate ester) on the H2O2 generating system itself.
Biochemical and biophysical research communications  •  1988  |  View Paper