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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Carbachol
supplement:
Homocysteine
Research Papers that Mention the Interaction
“ Homocysteine also dose-dependently inhibited insulinotropic responses to a range of glucose-dependent secretagogues including nutrients (alanine, arginine, 2-ketoisocaproate), hormones (glucagon-like peptide-1 (7-36)amide, gastric inhibitory polypeptide and cholecystokinin-8), neurotransmitter ( carbachol ), drug (tolbutamide) as well as a depolarising concentration of KCl or elevated Ca2+.”
Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.“ Carbachol and arecoline attenuated the effects of homocysteine on genes in the death receptor pathway, in the mitochondrial pathway and in the downstream pathway.”
Non-neuronal muscarinic receptor activation prevents apoptosis of endothelial cells induced by homocysteine.
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