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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Fluoride enhanced basal production of 3H‐inositol phosphates in membranes prepared from brain cortical slices that had been prelabeled with [3H]inositol, but inhibited the stimulation elicited by carbachol in the presence of GTPγS. However in both cases fluoride depleted [3H]PtdIns4P content by 95%.”
Fluoride-induced depletion of polyphosphoinositides in rat brain cortical slices: a rationale for the inhibitory effects on phospholipase C“Consequently, under conditions where breakdown of polyphosphoinositides by … was dependent on PtdIns kinase activity, fluoride inhibited activation …[S] plus carbachol of phospholipase C. When conditions allowed direct breakdown of PtdIns and precluded PtdIns kinase activity, … effects of fluoride and GTP[S] plus carbachol on phospholipase C activity were additive.”
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