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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carbachol and Edetic Acid

supplement:

Edetic Acid

Research Papers that Mention the Interaction

However, when EDTA (1 mM) was added, the stimulating effect of carbachol alone or carbachol + K+ was almost completely prevented.
Neurochemical Research  •  2004  |  View Paper
Furthermore, the inhibitory effect of carbachol was attenuated by the presence of 1 mM EDTA in media for pretreatment, suggesting that intracellular pathways activated by pancreatic secretagogues may be responsible for somatostatin receptor modulation.
Pancreas  •  1988  |  View Paper
When 1 mM EDTA was present in the pretreatment medium, the inhibitory effect of carbachol or CCK8 was partially abolished, suggesting that an intracellular process to modulate somatostatin binding is dependent on Ca2+.
Nihon Naibunpi Gakkai zasshi  •  1986  |  View Paper
Omission of calcium ions from the incubation medium and pre‐treatment of the slices with ethylenediaminetetraacetic acid (EDTA) caused a marked reduction in alkaline phosphatase secretion induced by carbamylcholine but had no effect on incorporation of P32 into phospholipids.
Journal of cellular physiology  •  1971  |  View Paper