Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Carbachol and Calcium Supplement

Research Papers that Mention the Interaction

Chronic application of the mAchR agonist, carbachol (Cch), induces Arc transcription via ERK signaling and release of calcium from IP3-sensitive stores.
The Journal of Biological Chemistry  •  2012  |  View Paper
Chelation of calcium also inhibited MAPK activation by carbachol.
Glia  •  2001  |  View Paper
Han et al.20 reported that the muscarinic receptor agonist carbachol inhibited the Ca current stimulated by isoproterenol in myocytes from wild-type mice, but not in myocytes isolated from NOS3-KO mice.
Journal of cardiovascular electrophysiology  •  2001  |  View Paper
Taken together, these results suggest that carbachol and guanine nucleotides regulate the activation of a cation channel that conducts calcium.
The Journal of Membrane Biology  •  1997  |  View Paper
Carbachol stimulated a transient followed by a sustained increase in intracellular calcium.
The Journal of pharmacology and experimental therapeutics  •  1990  |  View Paper
The Ca2+ antagonist , nifedipine, inhibited the elevation in [Ca2+]i induced by 1-10 microM carbachol (CCh), but had no inhibitory effect on that induced by 30 and 100 microM CCh.
Life sciences  •  2007  |  View Paper
In the human submandibular ductal cell line (HSG) thapsigargin and carbachol stimulated Ca2+ release from the internal Ca2+ pool , resulting in the activation of capacitatively regulated Ca2+ entry (CRCE).
Pflügers Archiv  •  2004  |  View Paper
In addition, if Ca2+ is released from a caged Ca2+ compound after a UV pulse, the resulting Ca2+ peak is much larger in the presence of CCh than in its absence.
The Journal of Biological Chemistry  •  2003  |  View Paper
OBJECTIVE We hypothesized that the release of calcium from intracellular stores contributes to the contractions produced by the agonists oxytocin, carbachol , and prostaglandin F(2 )(alpha ) in human myometrium.
American journal of obstetrics and gynecology  •  1999  |  View Paper
Carbachol increased intracellular calcium in a dose-dependent manner; as did oxotremorine-M, aceclidine, and pilocarpine.
Experimental eye research  •  1996  |  View Paper
Show More