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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Captopril
supplement:
Diallyl Disulfide
Research Papers that Mention the Interaction
“The protective effects of DADS may be due to its ability to decrease metabolic activation of CP by inhibiting CYP2C11 and inducing CYP3A1, and its potent antioxidant activity and antiapoptotic effects occurred via the Nrf-2-antioxidant response element pathway.”
Mechanism for the protective effect of diallyl disulfide against cyclophosphamide acute urotoxicity in rats.“In contrast, DADS pretreatment effectively attenuated the testicular toxicity caused by CP , including decreased sperm head count, epididymal sperm motility, and epididymal index and increased histopathological alterations in the testis and epididymis.”
“These results indicate that DADS attenuates testicular toxicity induced by CP in rats.”
Protective effect of diallyl disulfide on cyclophosphamide-induced testicular toxicity in rats
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