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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Captopril and Carrageenan



Research Papers that Mention the Interaction

It is concluded that inhibition of ACE by captopril enhanced the early production of endogenous BK and the edema formation induced by carrageenan through a B2 receptor-mediated mechanism.
Peptides  •  1996  |  View Paper
Intraperitoneal administration of captopril (10 mg/kg) caused a marked reduction (by 98%) in levels of [1-5]BK in exudates 3 hr after administration of carrageenan.
Biochemical pharmacology  •  1993  |  View Paper
2 Captopril , an inhibitor of kininase 2, increased the level of kinins and the volume of the exudates after carrageenin treatment.
British journal of pharmacology  •  1990  |  View Paper
1 Hind paw oedema in rats, measured by plethysmography or extravasation of Evans Blue dye into the skin, after subplantar injection of submaximal doses of carrageenin (1–100 μg) was significantly increased for 4 h during kininase II inhibition with captopril (1 mg kg−1, s.c.).
3 The pain threshold of the paw, injected with carrageenin (1 μg) was lowered significantly after subcutaneous administration of captopril (1 mg kg−1).
British journal of pharmacology  •  1984  |  View Paper