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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Captopril and Carnitine



Research Papers that Mention the Interaction

The catalytic efficiency (V max/K m ) of CPT I in mutants A478G and C608A and all Met593 mutants toward carnitine as substrate was clearly increased.
The Journal of Biological Chemistry  •  2003  |  View Paper
In the carnitine-depleted rats, CP induced dramatic increases in CK-MB and LDH levels, carnitine clearance and intramitochondrial acetyl-CoA/CoA-SH, as well as progressive reduction in total carnitine and ATP in cardiac tissues.
Chemotherapy  •  2010  |  View Paper
In carnitine-depleted rats, CP resulted in dramatic increase in serum nephrotoxicity indices and acetyl-CoA and induced progressive reduction in total carnitine , CoA-SH and ATP as well as severe histopathological lesions in kidney tissues.
Clinical and Experimental Nephrology  •  2010  |  View Paper