Possible Interaction: Captopril and Calcium Supplement

“ Calcium was subnormal (P < 0.0001), but increased to the reference range during captopril treatment.”

“Pretreatment of myocytes with captopril (exposure and then wash) inhibited Ca2+ elevation elicited by RDSs or NO, indicating that captopril is an effective, membrane-permeable intracellular reducing agent.”

“ CP agent enhanced with Ca (CPCa) also caused Ca enamel uptake.”

“Urinary excretion of calcium and phosphorus markedly increased in db/db mice in response to captopril.”

“In conclusion, high dietary Ca increased pH in gizzard and ileum and interfered with the AID of P and CP.”

“ Captopril significantly decreased Zn concentration in liver, Cu concentration in liver, adrenals, jejunum, urine and hair and Mg concentrations in blood and urine.”

“In the presence of captopril , an inhibitor of the angiotensin converting enzyme, the increase in calcium caused by AngI was abolished in VSMC cultures and the contractile effect of this peptide in aortic rings was strongly decreased, whereas the responses to AngII remained unaffected.”

“ Captopril , hydralazine, and verapamil may have a common ability to reduce intracellular calcium and therefore inhibit DNA synthesis.”

“A high calcium value during AP or CP should always draw suspicion and warrants corresponding investigations in search of endocrine or malignant cause.”

“ Calcium apparently was artificially released upon homogenization, to a progressively greater extent in older cotyledons, and severely inhibited CPT and EPT activities.”