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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Captopril
supplement:
Alpha-lipoic acid
Research Papers that Mention the Interaction
“ CP administration distinctly triggered the apoptotic and necrotic cell death, and LA pretreatment affected cell death by decreasing the number of apoptotic and necrotic cells.”
“The results of this study illustrate the protective effect of LA on the CA and apoptosis induced by CP in the erythropoietic system of rats.”
Modification of cyclophosphamide-induced clastogenesis and apoptosis in rats by alpha-lipoic acid.“In rats injected with CP, the frequency of MNPCEs in bone marrow and peripheral blood was increased significantly in comparison with the controls, and in rats treated with lipoic acid and CP , the number of MNPCEs was decreased significantly in comparison to those given CP alone.”
“Our results illustrate the protective effect of lipoic acid on the in vivo clastogenicity induced by CP.”
“These results suggest that patients taking combinations of captopril and LA , either as combination therapy or in the form of INV-159 or INV-161, may also benefit from significant protection against cerebral infarction.”
Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model
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