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Possible Interaction: Capsaicin and Vasodilator Agents

Research Papers that Mention the Interaction

Pretreatment with capsaicin (1 mumol/L for 20 minutes) significantly shortened the duration of vasodilator response to ACh but did not affect the initial rapid phase of ACh-induced vasodilation.
Circulation research  •  1995  |  View Paper
Similarly, the capsaicin denervation also significantly attenuated the vasodilatory and the esophagoprotective effects of Ang-(1-7).
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  2014  |  View Paper
Using a non-invasive laser Doppler velocimetry technique to measure skin blood flow in the rat skin, we have shown that chronic treatment with capsaicin inhibited the vasodilator response to a non-pathological, local heat (44°C, 20 min duration) stimulus.
Agents and Actions  •  2005  |  View Paper
These findings suggest that the hyperemic effect of acute administration of capsaicin may be related to the stimulation of afferent sensory nerves and release of vasodilatory peptides.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
Capsaicin pretreatment significantly attenuated the vasodilator response.
Life sciences  •  1989  |  View Paper
These results indicate that, while capsaicin releases and depletes some vasodilator peptides from perivascular nerves, the powerful direct vasoconstrictor effect overwhelms the vasodilator effects in large cerebral arteries of cats.
Archives internationales de pharmacodynamie et de therapie  •  1988  |  View Paper