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Last Updated: a year ago

Possible Interaction: Capsaicin and Sincalide

supplement:

Capsaicin

Research Papers that Mention the Interaction

CCK-8 at 5 and 17 pmol·kg⁻¹·min⁻¹ reduced food intake during the 3-h infusion period by 39 and 71% in VEH rats and 7 and 18% in CAP rats.
CCK-8 was much less effective in reducing food intake in CAP vs. VEH rats.
American journal of physiology. Endocrinology and metabolism  •  2014  |  View Paper
In contrast, repeated oral administrations of camostat or intraperitoneal injections of CCK-8 significantly increased pancreatic wet weight in both capsaicin-treated and control rats.
American journal of physiology. Gastrointestinal and liver physiology  •  2003  |  View Paper
Capsaicin locally applied in duodenal mucosa significantly decreased CCK-8 response, whereas mucosal exposure to lidocaine completely blocked CCK-8 response.
Regulatory Peptides  •  1999  |  View Paper
The gastric mucosal hyperemic … low dose of CCK-8 (0.04 nmol/min iv infusion for 7 min) was abolished by inhibition of nitric oxide synthesis with NG-… methyl ester (15 mg/kg iv) and significantly blunted by defunctionalization of afferent neurons with a neurotoxic dose of capsaicin (125 …).
The American journal of physiology  •  1996  |  View Paper
Intraperitoneal CCK-8 markedly inhibited food intake and gastric emptying, and both effects were significantly attenuated in capsaicin-treated rats, indicating that capsaicin treatment successfully ablated vagal afferent fibers.
The American journal of physiology  •  1996  |  View Paper
In separate studies we demonstrated that gastroduodenal but not jejunal application of capsaicin for 30 min abolished pancreatic protein secretion in response to physiological doses of CCK-8.
Similarly perivagal treatment with a sensory neurotoxin, capsaicin , caused a complete inhibition of pancreatic protein secretion in response to CCK-8 infusion.
The Journal of clinical investigation  •  1993  |  View Paper
Suppression of sham feeding induced by CCK-8 was significantly attenuated in rats treated with capsaicin.
The American journal of physiology  •  1988  |  View Paper
The capsaicin treatment significantly attenuated the decrease in intragastric pressure in urethan-anesthetized rats in response to CCK-8 (0.1-100 pmol iv) compared with vehicle-treated controls.
The American journal of physiology  •  1988  |  View Paper
Suppression of feeding by cholecystokinin octapeptide (CCK OP) was attenuated after systemic pretreatment with capsaicin.
The American journal of physiology  •  1985  |  View Paper